Description

Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Bromo-8-Methyl-2-(Methylthio)- is a high-purity, advanced pharmaceutical intermediate (API intermediate) belonging to the pyridopyrimidinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers developing targeted therapies, including kinase inhibitors for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the design and production of potent kinase inhibitors used in cancer research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Custom Synthesis Building Block: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and bioorganic synthesis.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Bromo-8-Methyl-2-(Methylthio)-
CAS No.	851756-48-4
Molecular Formula	C9H8BrN3OS
Molecular Weight	286.15 g/mol
Synonyms	6-Bromo-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one; 6-Bromo-8-methyl-2-(methylsulfanyl)-8H-pyrido[2,3-d]pyrimidin-7-one; 851756-48-4; 6-Bromo-8-methyl-2-methylsulfanyl-pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-bromo-8-methyl-2-(methylthio)-; 6-Bromo-8-methyl-2-(methylthio)-7,8-dihydropyrido[2,3-d]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our Pyrido[2,3-D]Pyrimidin-7(8H)-One, 6-Bromo-8-Methyl-2-(Methylthio)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.