Description

4-Chloro-3,6-Difluoro-Pyridine-2-Carboxylic Acid is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-3,6-Difluoro-Pyridine-2-Carboxylic Acid
CAS No.	851386-44-2
Molecular Formula	C6H2ClF2NO2
Molecular Weight	193.54 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-chloro-3,6-difluoro-; 4-Chloro-3,6-difluoropicolinic acid; 3,6-Difluoro-4-chloropyridine-2-carboxylic acid; 4-Chloro-3,6-difluoro-2-pyridinecarboxylic acid; Diflufenzopyr intermediate; Halogenated picolinic acid derivative
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3,6-Difluoro-Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain traceability and documentation in line with cGMP principles for advanced intermediates, ensuring the material meets the exacting standards required for pharmaceutical and agrochemical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container must be kept tightly sealed due to the compound's sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.