Description

2,3-Difluoro-4-Iodopyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the difluoro-iodopyridine moiety can enhance biological activity and environmental stability.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transition metal-catalyzed processes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, where halogenated pyridines modify charge transport properties.
• Chemical Biology Probe: Utilized as a versatile handle for bioconjugation and labeling in the design of molecular probes and diagnostic agents.

Basic Information

Product Name	2,3-Difluoro-4-Iodopyridine
CAS No.	851386-34-0
Molecular Formula	C5H2F2IN
Molecular Weight	256.98 g/mol
Synonyms	4-Iodo-2,3-difluoropyridine; 2,3-Difluoro-4-iodopyridine; Pyridine, 2,3-difluoro-4-iodo-; 851386-34-0; 4-Iodo-2,3-difluoropyridine; 2,3-Difluoropyridin-4-yl iodide
EINECS	Contact for details

Quality Control

We supply 2,3-Difluoro-4-Iodopyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, GC, NMR, and mass spectrometry are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat and incompatible materials. The container should be kept tightly sealed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC/GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.