Description

3-Pyridinecarbonitrile, 2-Amino-3,4,5,6-Tetrahydro-5-Methyl-6-Oxo- is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing complex heterocyclic cores.
• Agrochemical Research: Serves as a building block for developing new pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: A potential monomer or precursor for creating advanced polymers and functional materials with specific electronic or photonic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory chemistry projects.
• Fine Chemical Production: Integrated into multi-step synthetic routes for high-value, low-volume specialty chemicals.

Basic Information

Product Name	3-Pyridinecarbonitrile, 2-Amino-3,4,5,6-Tetrahydro-5-Methyl-6-Oxo-
CAS No.	851322-21-9
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	2-Amino-5-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile; 2-Amino-5-methyl-6-oxo-1,4,5,6-tetrahydronicotinonitrile; 5-Methyl-2-amino-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile; 6-Oxo-2-amino-5-methyl-1,4,5,6-tetrahydropyridine-3-carbonitrile; 1,4,5,6-Tetrahydro-2-amino-5-methyl-6-oxo-3-pyridinecarbonitrile; 851322-21-9 (CAS Name); Tetrahydro-2-amino-5-methyl-6-oxonicotinonitrile
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonitrile, 2-Amino-3,4,5,6-Tetrahydro-5-Methyl-6-Oxo- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.