Description

6-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid is a high-value, multi-functional organic building block characterized by its unique trifluoromethoxy-substituted aromatic ring system. This compound is essential for advanced chemical synthesis, offering a versatile scaffold for introducing specific steric and electronic properties into target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a core structure for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands in catalysis and material science applications.
• Functional Material Development: Incorporated into polymers and advanced organic materials to impart specific chemical resistance or optical properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	6-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid
CAS No.	851266-74-5
Molecular Formula	C13H8F3NO3
Molecular Weight	283.21 g/mol
Synonyms	6-[4-(Trifluoromethoxy)phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-[4-(trifluoromethoxy)phenyl]-; Nicotinic acid, 6-[4-(trifluoromethoxy)phenyl]-; 6-(4-Trifluoromethoxyphenyl)nicotinic acid; 851266-74-5
EINECS	Contact for details

Quality Control

Our 6-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.