Description

1H-Imidazol-5-Amine, 4-(2-Methyl-4-Pyridinyl)- is a high-purity, heterocyclic organic compound featuring a fused imidazole-pyridine structure, serving as a critical advanced pharmaceutical intermediate. This compound matters because it provides a versatile and reactive scaffold for the synthesis of novel drug candidates, particularly in targeted therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors, anti-cancer agents, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Used in the development of enzyme assays and probes for biological pathway analysis.
• Agrochemical Research: Intermediate for developing novel active ingredients with potential fungicidal or pesticidal properties.
• Material Science: Precursor for synthesizing specialized ligands used in catalysis and coordination chemistry.

Basic Information

Item	Details
Product Name	1H-Imidazol-5-Amine, 4-(2-Methyl-4-Pyridinyl)-
CAS No.	851262-41-4
Molecular Formula	C9H10N4
Molecular Weight	174.20 g/mol
Synonyms	4-(2-Methylpyridin-4-yl)-1H-imidazol-5-amine; 5-Amino-4-(2-methyl-4-pyridinyl)imidazole; 4-(2-Methyl-4-pyridinyl)-1H-imidazol-5-amine; 1H-Imidazol-5-amine, 4-(2-methyl-4-pyridinyl)-; 851262-41-4; 4-(2-Methylpyridin-4-yl)-1H-imidazol-5-ylamine
EINECS	Contact for details

Quality Control

Our 1H-Imidazol-5-Amine, 4-(2-Methyl-4-Pyridinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.