Description

[3-Chloro-2-Oxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]Acetic Acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridinyl acetic acid core with chloro, oxo, and trifluoromethyl substituents. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific halogenated and fluorinated motifs. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral therapies.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Chemical Synthesis Reagent: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening in drug discovery.
• Material Science Applications: Potential use in the synthesis of specialty polymers or liquid crystals, where its aromatic and halogenated structure can impart specific electronic or physical properties.

Basic Information

Product Name	[3-Chloro-2-Oxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]Acetic Acid (Saltdata: Free)
CAS No.	851208-01-0
Molecular Formula	C8H5ClF3NO3
Molecular Weight	255.58 g/mol
Synonyms	2-[(3-Chloro-2-oxo-5-(trifluoromethyl)-1(2H)-pyridinyl)]acetic acid; 1(2H)-Pyridineacetic acid, 3-chloro-2-oxo-5-(trifluoromethyl)-; 3-Chloro-2-oxo-5-(trifluoromethyl)-1,2-dihydropyridine-1-acetic acid; 3-Chloro-5-(trifluoromethyl)-2-oxo-1,2-dihydropyridin-1-ylacetic acid; 851208-01-0; (3-Chloro-2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our production of [3-Chloro-2-Oxo-5-(Trifluoromethyl)-1(2H)-Pyridinyl]Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.