Description

3,4-Dichloro-5-Fluoropyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring a fluoropyridine core.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialized polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the pyridine moiety.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry research in both industrial and academic settings.

Basic Information

Product Name	3,4-Dichloro-5-Fluoropyridine
CAS No.	851179-02-7
Molecular Formula	C5H2Cl2FN
Molecular Weight	165.98 g/mol
Synonyms	5-Fluoro-3,4-dichloropyridine; 3,4-Dichloro-5-fluoropyridine; 5-Fluoro-3,4-dichloropyridine; Pyridine, 3,4-dichloro-5-fluoro-; 851179-02-7
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.