Description

3-Chloro-2,5-Difluoropyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create specialized ligands for transition metal catalysis in cross-coupling and other fine chemical reactions.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	3-Chloro-2,5-Difluoropyridine
CAS No.	851179-00-5
Molecular Formula	C5H2ClF2N
Molecular Weight	149.53 g/mol
Synonyms	2,5-Difluoro-3-chloropyridine; 3-Chloro-2,5-difluoropyridine; Pyridine, 3-chloro-2,5-difluoro-; 851179-00-5; 3-Chloro-2,5-difluoro-pyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,5-Difluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.