Description

1-Isopropyl-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid CAS NO 851175-95-6 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in areas such as oncology and anti-inflammatory therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially kinase inhibitors.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct sophisticated molecular architectures for biological screening.
• Medicinal Chemistry Research: Essential for structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Research Organization (CRO) & Contract Development and Manufacturing Organization (CDMO) Supply: Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug discovery methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	1-Isopropyl-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	851175-95-6
Molecular Formula	C₁₆H₁₅N₃O₂
Molecular Weight	281.31 g/mol
Synonyms	1-Isopropyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyrazolo[3,4-b]pyridinecarboxylic acid, 1-(1-methylethyl)-6-phenyl-; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(1-methylethyl)-6-phenyl-; 851175-95-6; 1-Isopropyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Phenyl-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry best practices for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.