Description

n-(6-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity, iodinated pyridine derivative designed for advanced chemical synthesis and research. This compound serves as a critical building block in pharmaceutical and agrochemical research, where its unique halogenated structure enables the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	n-(6-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	851102-44-8
Molecular Formula	C10H13IN2O
Molecular Weight	304.13 g/mol
Synonyms	2,2-Dimethyl-N-(6-iodopyridin-2-yl)propanamide; N-(6-Iodo-2-pyridinyl)-2,2-dimethylpropanamide; 6-Iodo-N-(2,2-dimethylpropanoyl)pyridin-2-amine; Pivalamido-6-iodopyridine; 2-Iodo-6-pivalamidopyridine; Propanamide, N-(6-iodo-2-pyridinyl)-2,2-dimethyl-; 851102-44-8
EINECS	Contact for details

Quality Control

Our n-(6-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.