Description

6-Iodo-Pyridine-2-Carboxylic Acid Hydrazide is a versatile and highly functionalized heterocyclic building block, primarily valued for its role as a key intermediate in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a reactive hydrazide group, makes it a critical precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on the synthesis of novel active ingredients, particularly in the development of targeted therapies and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in the development of kinase inhibitors, anti-infectives, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core and iodine atom are leveraged for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functional organic materials, such as metal-organic frameworks (MOFs) or organic semiconductors, due to its ability to form coordination complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, leveraging the reactivity of the hydrazide group for bioconjugation.

Basic Information

Product Name	6-Iodo-Pyridine-2-Carboxylic Acid Hydrazide
CAS No.	851102-43-7
Molecular Formula	C6H6IN3O
Molecular Weight	263.04 g/mol
Synonyms	6-Iodopyridine-2-carbohydrazide; 2-Pyridinecarboxylic acid, 6-iodo-, hydrazide; 6-Iodo-2-pyridinecarboxylic acid hydrazide; 6-Iodopicolinohydrazide; Picolinohydrazide, 6-iodo-; 851102-43-7; 6-Iodopyridine-2-carboxylic hydrazide
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-Pyridine-2-Carboxylic Acid Hydrazide is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment. For long-term storage, consider maintaining the material under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.