Description

(6-Iodo-Pyridin-2-Yl)-Methanol is a versatile iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the iodine atom and the hydroxymethyl group, which allows for selective functionalization and coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological processes and target engagement.

Basic Information

Product Name	(6-Iodo-Pyridin-2-Yl)-Methanol
CAS No.	851102-41-5
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	2-(Hydroxymethyl)-6-iodopyridine; 6-Iodo-2-pyridinemethanol; (6-Iodo-2-pyridinyl)methanol; 2-Pyridinemethanol, 6-iodo-; 6-Iodopyridine-2-methanol; 6-Iodo-2-(hydroxymethyl)pyridine; 2-Hydroxymethyl-6-iodopyridine
EINECS	Contact for details

Quality Control

Our (6-Iodo-Pyridin-2-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.