Description

tert-Butyl 4-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate is a high-purity, protected heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a versatile synthetic intermediate, enabling the precise construction of complex molecular architectures through cross-coupling and functional group transformations. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyrrolopyridine core.
• Material Science: Serves as a precursor for organic electronic materials and functionalized ligands for catalysis.
• Cross-Coupling Reactions: The bromine atom at the 4-position makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of new chemical space in drug discovery programs.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 4-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate
CAS No.	850892-97-6
Molecular Formula	C12H13BrN2O2
Molecular Weight	297.15 g/mol
Synonyms	1-Boc-4-bromo-7-azaindole; 4-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester; 4-Bromo-1-(tert-butoxycarbonyl)-7-azaindole; tert-Butyl 4-bromo-7-azaindole-1-carboxylate; 4-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; 4-Bromo-1-Boc-7-azaindole; 1-(tert-Butoxycarbonyl)-4-bromo-1H-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.