Description

(E)-3-(4-Chlorophenyl)-1-(5-Fluoro-2-Hydroxyphenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct halogenated aromatic structure. This compound serves as a critical advanced intermediate in the research and development of novel pharmaceutical agents and agrochemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, anti-inflammatory, and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its halogenated chalcone scaffold for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and protein-ligand interactions.
• Material Science Precursor: Potential intermediate for synthesizing organic semiconductors and non-linear optical (NLO) materials due to its conjugated system.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(E)-3-(4-Chlorophenyl)-1-(5-Fluoro-2-Hydroxyphenyl)Prop-2-En-1-One
CAS No.	850799-78-9
Molecular Formula	C15H10ClFO2
Molecular Weight	276.69 g/mol
Synonyms	(E)-3-(4-Chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one; (E)-1-(5-Fluoro-2-hydroxyphenyl)-3-(4-chlorophenyl)-2-propen-1-one; 2-Propen-1-one, 1-(5-fluoro-2-hydroxyphenyl)-3-(4-chlorophenyl)-, (E)-; Chalcone derivative, 4'-chloro-2'-hydroxy-5-fluoro; 5-Fluoro-2-hydroxy-4'-chlorochalcone; 850799-78-9; Halogenated chalcone intermediate
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Chlorophenyl)-1-(5-Fluoro-2-Hydroxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.