Description

5-Chloro-2-Methyl-3-(Methylthio)-1H-Pyrrolo[3,2-B]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex pyrrolopyridine core, functionalized with chloro, methyl, and methylthio groups, makes it a versatile intermediate for constructing sophisticated molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-rich pyrrolopyridine system.
• Chemical Synthesis: Employed in academic and industrial R&D for complex coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for library synthesis in medicinal chemistry.
• Ligand and Catalyst Development: Its structure can be modified to create novel ligands for transition metal catalysis, useful in asymmetric synthesis and polymerization processes.

Basic Information

Product Name	5-Chloro-2-Methyl-3-(Methylthio)-1H-Pyrrolo[3,2-B]Pyridine
CAS No.	850785-54-5
Molecular Formula	C9H9ClN2S
Molecular Weight	212.70 g/mol
Synonyms	5-Chloro-2-methyl-3-(methylthio)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 5-chloro-2-methyl-3-(methylthio)-; 850785-54-5; 5-Chloro-2-methyl-3-methylsulfanyl-1H-pyrrolo[3,2-b]pyridine; 3-(Methylthio)-5-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and production use. Our standard offering for this advanced intermediate typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥98% and ≥99%) available. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, and are produced in facilities adhering to ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.