Description

4-Chloro-5-Nitro-2-Hydroxypyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound, with the CAS number 850663-54-6, is valued for its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating specialized ligands, dyes, and functional polymers.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways in heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Chloro-5-Nitro-2-Hydroxypyridine
CAS No.	850663-54-6
Molecular Formula	C5H3ClN2O3
Molecular Weight	174.54 g/mol
Synonyms	2-Hydroxy-4-chloro-5-nitropyridine; 4-Chloro-5-nitropyridin-2-ol; 5-Nitro-4-chloro-2-pyridinol; 4-Chloro-5-nitro-2(1H)-pyridinone; 4-Chloro-5-nitropyridin-2(1H)-one; 2-Pyridinol, 4-chloro-5-nitro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Nitro-2-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.