Description

1,6-Anhydro-2-Azido-2-Deoxy-4-o-[(1,1-Dimethylethyl)Diphenylsilyl]-β-D-Glucopyranose3-Acetate is a sophisticated, high-purity carbohydrate derivative and a key protected intermediate in advanced organic synthesis. Its value lies in its precisely engineered structure, featuring an anhydro bridge, an azido group, and a tert-butyldiphenylsilyl (TBDPS) protecting group, which provides exceptional selectivity and stability for complex multi-step reactions. This compound is essential for researchers and process chemists in the pharmaceutical and biotechnology sectors, particularly for the synthesis of novel nucleoside analogs, antiviral agents, and complex glycoconjugates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Used in the study and development of complex oligosaccharides, glycopeptides, and glycomimetics due to its protected and reactive functional groups.
• Antiviral Drug Development: Serves as a precursor in the research and production stages of antiviral compounds targeting viruses like HIV, hepatitis, and influenza.
• Glycoconjugate Synthesis: Employed in the preparation of structurally defined glycoconjugates for vaccine development and diagnostic applications.
• Chemical Biology Probes: Utilized to create labeled or modified sugars for investigating biological recognition and metabolic pathways.
• Process Chemistry Scale-up: Provides a reliable and high-quality intermediate for the pilot-scale and commercial-scale manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1,6-Anhydro-2-Azido-2-Deoxy-4-o-[(1,1-Dimethylethyl)Diphenylsilyl]-β-D-Glucopyranose3-Acetate
CAS No.	850637-35-3
Molecular Formula	C26H33N3O5Si
Molecular Weight	495.65 g/mol
Synonyms	1,6-Anhydro-2-azido-2-deoxy-4-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-glucopyranose 3-acetate; 4-O-(tert-Butyldiphenylsilyl)-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose 3-acetate; 1,6-Anhydro-2-azido-2-deoxy-4-O-(tert-butyldiphenylsilyl)-β-D-glucopyranose 3-acetate; TBDPS-protected 1,6-anhydro-2-azido-2-deoxy-glucose 3-acetate; 2-Azido-1,6-anhydro-2-deoxy-4-O-(tert-butyldiphenylsilyl)-β-D-glucopyranose 3-acetate; β-D-1,6-Anhydro-2-azido-2-deoxy-4-O-(t-butyldiphenylsilyl)glucopyranose 3-acetate
EINECS	Contact for details

Quality Control

Our 1,6-Anhydro-2-Azido-2-Deoxy-4-o-[(1,1-Dimethylethyl)Diphenylsilyl]-β-D-Glucopyranose3-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.