Description

3-Chloro-4-(n-Ethylcarbamoyl)Benzeneboronic Acid is a high-value boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing biphenyl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for palladium-catalyzed C-C bond formation with aryl or vinyl halides.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with complex aromatic backbones.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Can be utilized as a handle for bioconjugation or in the development of enzyme inhibitors and molecular probes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Chloro-4-(n-Ethylcarbamoyl)Benzeneboronic Acid
CAS No.	850589-40-1
Molecular Formula	C9H11BClNO3
Molecular Weight	227.45 g/mol
Synonyms	3-Chloro-4-(ethylcarbamoyl)phenylboronic acid; (3-Chloro-4-(ethylcarbamoyl)phenyl)boronic acid; 4-Borono-2-chloro-N-ethylbenzamide; B-[3-Chloro-4-[(ethylamino)carbonyl]phenyl]boronic acid; 850589-40-1; Benzeneboronic acid, 3-chloro-4-[(ethylamino)carbonyl]-; 3-Chloro-4-(ethylaminocarbonyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(n-Ethylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.