Description

5-Bromo-2-tert-Butoxy-Pyridine is a high-purity, versatile brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and tert-butoxy groups, which enable selective functionalization and serve as a protected intermediate for complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring halogenated pyridine scaffolds.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	5-Bromo-2-tert-Butoxy-Pyridine
CAS No.	850495-91-9
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	2-(tert-Butoxy)-5-bromopyridine; 5-Bromo-2-(tert-butoxy)pyridine; 5-Bromo-2-(1,1-dimethylethoxy)pyridine; 5-Bromo-2-(tert-butoxy)pyridine; 5-Bromo-2-tert-butoxypyridine; 5-Bromo-2-(tert-butyloxy)pyridine; 5-Bromo-2-(t-butoxy)pyridine; 5-Bromo-2-(tert-butoxy)pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-tert-Butoxy-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices. Our commitment to quality supports applications in GMP and ISO-certified environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.