Description

(R)-2-Butylsuccinic Acid-1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functional group versatility make it a critical precursor for constructing complex molecules with specific three-dimensional architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis, medicinal chemistry, and the development of active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific (R)-configured stereocenters.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex flavors, fragrances, and other specialty chemicals where stereochemical purity is paramount.
• Academic & Industrial Research: Utilized in methodological development and exploratory chemistry for novel synthetic routes and compound libraries.

Basic Information

Product Name	(R)-2-Butylsuccinic Acid-1-Methyl Ester
CAS No.	850411-21-1
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	(R)-1-Methoxy-1-oxo-2-butylsuccinate; (R)-2-Butyl-1,4-butanedioic acid 1-methyl ester; Methyl (R)-2-butylsuccinate; (R)-Methyl 2-butylsuccinate; (2R)-2-Butylbutanedioic acid methyl ester; (R)-2-(1-Methoxycarbonyl)propylpentanoic acid; (R)-Methyl hydrogen 2-butylsuccinate
EINECS	Contact for details

Quality Control

Our production of (R)-2-Butylsuccinic Acid-1-Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.