Description

Z-[2-Bromo-4-(2-Pyridin-3-Yl-Vinyl)-Phenoxy]-Acetic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its brominated styrylpyridine core. This compound matters as a critical building block in the synthesis of targeted small molecule therapeutics, offering precise chemical functionality for complex coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for developing novel drug candidates, particularly in oncology and CNS research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Chemical Biology Probe Development: Used to create molecular probes for studying protein-ligand interactions and cellular signaling pathways.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) to construct complex heterocyclic systems.
• Material Science Research: Investigated as a potential monomer or component for functional organic materials and polymers.
• Agrochemical Research: Serves as a starting point for developing new active ingredients with specific biological activity.

Basic Information

Product Name	Z-[2-Bromo-4-(2-Pyridin-3-Yl-Vinyl)-Phenoxy]-Acetic Acid tert-Butyl Ester
CAS No.	850411-11-9
Molecular Formula	C19H20BrNO3
Molecular Weight	390.27 g/mol
Synonyms	tert-Butyl 2-[2-bromo-4-[(E)-2-(pyridin-3-yl)ethenyl]phenoxy]acetate; (E)-tert-Butyl 2-(2-bromo-4-(2-(pyridin-3-yl)vinyl)phenoxy)acetate; Z-2-Bromo-4-(2-Pyridin-3-Yl-Vinyl)-Phenoxy Acetic Acid tert-Butyl Ester; 850411-11-9; Acetic acid, 2-[2-bromo-4-[(E)-2-(3-pyridinyl)ethenyl]phenoxy]-, 1,1-dimethylethyl ester; tert-Butyl (2E)-3-(3-bromo-4-{[(tert-butoxy)carbonyl]methoxy}phenyl)-2-propenoate (related structure); Bromostyrylpyridine acetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Z-[2-Bromo-4-(2-Pyridin-3-Yl-Vinyl)-Phenoxy]-Acetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and batch-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.