Description

3-(5-Bromo-Pyridin-3-Yl)-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester is a high-value brominated heterocyclic building block, specifically an oxadiazole derivative, designed for advanced pharmaceutical and agrochemical research and development. This compound is critical for medicinal chemists seeking to incorporate a halogenated, nitrogen-rich bicyclic scaffold into novel molecular entities to modulate biological activity and physicochemical properties. It is primarily utilized by R&D departments in pharmaceutical companies, agrochemical innovators, and contract research organizations (CROs) focused on synthesizing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole and bromopyridine motifs.
• Chemical Biology Probe Synthesis: Acts as a versatile building block for creating molecular probes to study enzyme function and protein-ligand interactions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-(5-Bromo-Pyridin-3-Yl)-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	850375-34-7
Molecular Formula	C10H8BrN3O3
Molecular Weight	298.09 g/mol
Synonyms	Ethyl 3-(5-bromopyridin-3-yl)-1,2,4-oxadiazole-5-carboxylate; 5-Bromo-3-(5-ethoxycarbonyl-[1,2,4]oxadiazol-3-yl)pyridine; 850375-34-7; 3-(5-Bromo-3-pyridyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(5-bromo-3-pyridinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(5-Bromo-Pyridin-3-Yl)-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical specifications are provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.