Description

4-Methyl 2-Thienyl Isocyanate is a specialized organic building block characterized by its reactive isocyanate group attached to a substituted thiophene ring. This compound matters for its role as a key intermediate in the synthesis of advanced heterocyclic compounds, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where the thienyl moiety can impart specific biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polymers with unique thermal or chemical resistance properties.
• Material Science Research: Employed in the development of advanced functional materials, including liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a reagent for bioconjugation and labeling of biomolecules due to the reactivity of the isocyanate group with amines and alcohols.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for clients in the life sciences sector.

Basic Information

Product Name	4-Methyl 2-Thienyl Isocyanate
CAS No.	850375-10-9
Molecular Formula	C6H5NOS
Molecular Weight	139.17 g/mol
Synonyms	2-Isocyanato-4-methylthiophene; 4-Methylthiophene-2-isocyanate; 4-Methyl-2-thienyl isocyanate; 2-Thienyl isocyanate, 4-methyl-; 4-Methyl-2-thiophene isocyanate; Isocyanic acid, 4-methyl-2-thienyl ester; 850375-10-9
EINECS	Contact for details

Quality Control

Our 4-Methyl 2-Thienyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.