Description

n-(6-Bromopyridin-3-Yl)-2,2-Difluoroacetamide is a high-purity bromopyridine derivative and a versatile chemical building block, essential for advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both a bromo-substituted pyridine ring and a difluoroacetamide moiety, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or liquid crystals.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up services for specialized chemical entities.
• Academic and R&D Laboratories: Used in fundamental chemical research to explore new reaction pathways and heterocyclic chemistry.

Basic Information

Product Name	n-(6-Bromopyridin-3-Yl)-2,2-Difluoroacetamide
CAS No.	850349-86-9
Molecular Formula	C7H5BrF2N2O
Molecular Weight	251.03 g/mol
Synonyms	2,2-Difluoro-N-(6-bromopyridin-3-yl)acetamide; 6-Bromo-3-pyridinyl-2,2-difluoroacetamide; N-(6-Bromo-3-pyridinyl)-2,2-difluoroacetamide; 850349-86-9; 2,2-Difluoroacetamide, N-(6-bromo-3-pyridinyl)-; Acetamide, 2,2-difluoro-N-(6-bromo-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our n-(6-Bromopyridin-3-Yl)-2,2-Difluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.