Description

5-Bromo-Spiro[Indan-2,2'-(1,3-Oxathiolane)] is a specialized spirocyclic organic compound featuring a brominated indan core fused with a 1,3-oxathiolane ring system. This unique molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in synthetic organic chemistry. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active compounds. The compound is supplied with a high level of purity to meet the stringent requirements of process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a key scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of specialty polymers and organic electronic materials due to its rigid, fused-ring structure.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex spirocyclic and heterocyclic molecules.
• Ligand and Catalyst Development: The bromine atom and sulfur/oxygen heteroatoms make it a candidate for developing novel ligands in catalytic systems.

Basic Information

Product Name	5-Bromo-Spiro[Indan-2,2'-(1,3-Oxathiolane)]
CAS No.	850349-52-9
Molecular Formula	C12H11BrOS
Molecular Weight	283.18 g/mol
Synonyms	5-Bromo-2,3-dihydrospiro[indene-2,2'-[1,3]oxathiolane]; 5-Bromospiro[indane-2,2'-[1,3]oxathiolane]; 5-Bromo-1H-indene-2-spiro-2'-[1,3]oxathiolane; 5-Bromo-spiro[indan-2,2'-[1,3]oxathiolane]; Spiro[indan-2,2'-[1,3]oxathiolane], 5-bromo-; 850349-52-9; 5-Bromo-1,3-oxathiolane-spiro-indan
EINECS	Contact for details

Quality Control

Our 5-Bromo-Spiro[Indan-2,2'-(1,3-Oxathiolane)] is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.