Description

(2-Bromo-Pyridin-3-Yloxy)-Acetic Acid Ethyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its reactive bromine and ester functionalities, which make it a versatile synthon for constructing complex heterocyclic molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	(2-Bromo-Pyridin-3-Yloxy)-Acetic Acid Ethyl Ester
CAS No.	850349-18-7
Molecular Formula	C9H10BrNO3
Molecular Weight	260.09 g/mol
Synonyms	Ethyl (2-bromopyridin-3-yloxy)acetate; 2-Bromo-3-pyridyloxyacetic Acid Ethyl Ester; Ethyl 2-[(2-bromopyridin-3-yl)oxy]acetate; Acetic acid, 2-[(2-bromo-3-pyridinyl)oxy]-, ethyl ester; 850349-18-7; (2-Bromo-3-pyridyloxy)acetic acid ethyl ester; 3-Pyridinol, 2-bromo-, O-acetate, ethyl ether
EINECS	Contact for details

Quality Control

Our (2-Bromo-Pyridin-3-Yloxy)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.