Description

3-Bromo-2,4-Dichloro-5-Nitropyridine is a high-purity halogenated and nitrated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique substitution pattern makes it a versatile and valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient pyridine core.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes, affinity labels, and bioconjugation reagents.
• Academic & Industrial R&D: Essential for methodological development in cross-coupling reactions, nucleophilic aromatic substitution (SNAr), and other catalytic transformations.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	3-Bromo-2,4-Dichloro-5-Nitropyridine
CAS No.	850180-82-4
Molecular Formula	C5HBrCl2N2O2
Molecular Weight	271.88 g/mol
Synonyms	3-Bromo-2,4-dichloro-5-nitropyridine; 2,4-Dichloro-3-bromo-5-nitropyridine; 5-Nitro-3-bromo-2,4-dichloropyridine; Pyridine, 3-bromo-2,4-dichloro-5-nitro-; 850180-82-4; 3-Br-2,4-Cl2-5-NO2-Pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Dichloro-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP development and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.