Description

6-Bromo-2-Fluoro-3-Hydroxypyridine is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic heterocyclic core.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-Hydroxypyridine
CAS No.	850142-72-2
Molecular Formula	C5H3BrFNO
Molecular Weight	191.99 g/mol
Synonyms	3-Hydroxy-6-bromo-2-fluoropyridine; 2-Fluoro-6-bromo-3-pyridinol; 6-Bromo-2-fluoro-3-pyridinol; 6-Bromo-2-fluoropyridin-3-ol; 850142-72-2; 3-Pyridinol, 6-bromo-2-fluoro-; Br-6, F-2, OH-3 substituted pyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-Fluoro-3-Hydroxypyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and elemental analysis to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.