Description

5-Phenyl-7-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyridin-2-amine is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical assays and for studying protein-ligand interactions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel synthetic route exploration.
• Custom Synthesis: A starting material for the bespoke production of complex molecules for client-specific applications.

Basic Information

Product Name	5-Phenyl-7-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyridin-2-amine
CAS No.	850021-29-3
Molecular Formula	C15H10F3N3S
Molecular Weight	321.32 g/mol
Synonyms	5-Phenyl-7-(trifluoromethyl)thiazolo[4,5-b]pyridin-2-amine; 2-Amino-5-phenyl-7-(trifluoromethyl)thiazolo[4,5-b]pyridine; 7-(Trifluoromethyl)-5-phenyl[1,3]thiazolo[4,5-b]pyridin-2-amine; 850021-29-3; Thiazolo[4,5-b]pyridin-2-amine, 5-phenyl-7-(trifluoromethyl)-; AKOS005258156
EINECS	Contact for details

Quality Control

Our 5-Phenyl-7-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyridin-2-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.