Description

4-Bromo-2,3,6-trifluoropyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, where halogenated pyridines modify charge transport properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	4-Bromo-2,3,6-trifluoropyridine
CAS No.	849937-93-5
Molecular Formula	C5HBrF3N
Molecular Weight	209.96 g/mol
Synonyms	2,3,6-Trifluoro-4-bromopyridine; 4-Bromo-2,3,6-trifluoropyridine; Pyridine, 4-bromo-2,3,6-trifluoro-; 849937-93-5; 4-Bromo-2,3,6-trifluoro-pyridin; 4-Brom-2,3,6-trifluorpyridin
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3,6-trifluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.