Description

2-Methylsulfanyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because its boronic ester functionality enables critical carbon-carbon bond-forming reactions, such as the Suzuki-Miyaura cross-coupling, which is fundamental to constructing complex molecular architectures. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the efficient synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation tools for target identification and validation.
• Ligand & Catalyst Development: Utilized to synthesize novel pyridine-based ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Product Name	2-Methylsulfanyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine
CAS No.	849934-89-0
Molecular Formula	C13H20BNO2S
Molecular Weight	265.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methylthio)pyridine; 2-(Methylthio)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methylsulfanyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol 2-(Methylthio)pyridine-5-boronate; 2-(Methylsulfanyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Methylsulfanyl-5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.