Description

5-Bromo-2-Ethoxy-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique molecular architecture, featuring bromine, ethoxy, and trifluoromethyl substituents on a pyridine core, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients, as well as by material scientists developing specialty chemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers where its halogen and fluorine content can modify electronic properties and stability.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-Bromo-2-Ethoxy-3-(Trifluoromethyl)Pyridine
CAS No.	849934-83-4
Molecular Formula	C8H7BrF3NO
Molecular Weight	270.05 g/mol
Synonyms	5-Bromo-2-ethoxy-3-(trifluoromethyl)pyridine; 2-Ethoxy-5-bromo-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-bromo-2-ethoxypyridine; Pyridine, 5-bromo-2-ethoxy-3-(trifluoromethyl)-; 849934-83-4; 5-Br-2-EtO-3-CF3-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethoxy-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and documentation, including detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material meets the stringent requirements for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.