Description

3-(5-Piperidin-4-Yl-1,2,4-Oxadiazol-3-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining piperidine, oxadiazole, and pyridine moieties. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Serves as a building block for compounds designed to modulate specific enzyme activity.
• Kinase Inhibitor Synthesis: Employed in the creation of potential kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	3-(5-Piperidin-4-Yl-1,2,4-Oxadiazol-3-Yl)Pyridine
CAS No.	849925-01-5
Molecular Formula	C12H14N4O
Molecular Weight	230.27 g/mol
Synonyms	3-(5-(Piperidin-4-yl)-1,2,4-oxadiazol-3-yl)pyridine; 3-[5-(4-Piperidinyl)-1,2,4-oxadiazol-3-yl]pyridine; Pyridine, 3-[5-(4-piperidinyl)-1,2,4-oxadiazol-3-yl]-; 849925-01-5; 4-(3-Pyridin-3-yl-1,2,4-oxadiazol-5-yl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(5-Piperidin-4-Yl-1,2,4-Oxadiazol-3-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with full traceability and can support development with analytical method transfer and validation data as required for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.