Description

(6-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-value, protected heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, serving as a versatile intermediate for cross-coupling reactions and further functionalization. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce iodine and protected amine functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the reactivity of the iodine substituent.
• Material Science: Serves as a precursor for creating functionalized ligands and complex organic frameworks for advanced materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Biology: Used in the synthesis of probes and labeled compounds for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(6-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	849830-17-7
Molecular Formula	C10H13IN2O2
Molecular Weight	320.13 g/mol
Synonyms	tert-Butyl (6-iodopyridin-2-yl)carbamate; N-Boc-2-Amino-6-iodopyridine; 2-((tert-Butoxycarbonyl)amino)-6-iodopyridine; 6-Iodo-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; Boc-2-Amino-6-iodopyridine; N-Boc-6-iodopyridin-2-amine; (6-Iodo-2-pyridinyl)carbamic acid tert-butyl ester; 2-Iodo-6-((tert-butoxycarbonyl)amino)pyridine
EINECS	Contact for details

Quality Control

Our (6-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation (by 1H NMR and IR), and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (1H NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.