Description

2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid is a high-value heterocyclic building block with a fused pyrrolopyridine core. This compound is critical for medicinal chemistry research and development, serving as a versatile scaffold for creating novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The fused bicyclic structure makes it a valuable core for developing potential kinase inhibitors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke synthetic routes.
• Agrochemical Research: Potential intermediate in the development of new agrochemicals and plant protection agents.

Basic Information

Product Name	2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid
CAS No.	849805-79-4
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	5-Carboxy-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 2,3-dihydro-; 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 2,3-dihydro-1H-; 849805-79-4; AI3-63500; SCHEMBL11827527; ZINC000003799756
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.