Description

2-{4-(Trifluoromethyl)Phenyl}-4-Pyridinamine is a high-value, fluorinated aromatic amine building block. This compound matters for its unique trifluoromethylphenyl-pyridinamine scaffold, which is critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as ligands for catalysts or monomers for specialty polymers.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-{4-(Trifluoromethyl)Phenyl}-4-Pyridinamine
CAS No.	849680-65-5
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]pyridin-4-amine; 4-Amino-2-[4-(trifluoromethyl)phenyl]pyridine; 2-(4-Trifluoromethylphenyl)-4-aminopyridine; 4-Pyridinamine, 2-[4-(trifluoromethyl)phenyl]-; 849680-65-5; 2-(4-(Trifluoromethyl)phenyl)pyridin-4-amine
EINECS	Contact for details

Quality Control

Our 2-{4-(Trifluoromethyl)Phenyl}-4-Pyridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride sources; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.