Description

3,5-Bis-Boc-Aminopyridine is a high-purity, protected amine derivative widely used as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in facilitating complex multi-step syntheses, particularly in the development of active pharmaceutical ingredients (APIs) and sophisticated agrochemicals, where protecting group chemistry is essential. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other nitrogen-rich bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides that require pyridine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs) with specific binding sites.
• Peptide Mimetics: Utilized in the design and synthesis of peptidomimetics where the Boc-protected amine is crucial for selective deprotection strategies.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in fine chemical production.

Basic Information

Product Name	3,5-Bis-Boc-Aminopyridine
CAS No.	849160-50-5
Molecular Formula	C₁₆H₂₅N₃O₄
Molecular Weight	323.39 g/mol
Synonyms	3,5-Bis(tert-butoxycarbonylamino)pyridine; 3,5-Bis[(tert-butoxycarbonyl)amino]pyridine; 3,5-Di-Boc-aminopyridine; Pyridine, 3,5-bis[[(1,1-dimethylethoxy)carbonyl]amino]-; 3,5-Bis-Boc-amino-pyridine; 3,5-Di-tert-butoxycarbonylaminopyridine; N3,N5-Bis(tert-butoxycarbonyl)pyridine-3,5-diamine
EINECS	Contact for details

Quality Control

Our 3,5-Bis-Boc-Aminopyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.