Description

5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. Its core value lies in its functionalized pyrrolopyridine scaffold, which is crucial for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel kinase inhibitors and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase-targeted therapies in oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science: Potential building block for organic electronic materials and ligands in catalytic systems due to its electron-rich heterocyclic structure.

Basic Information

Item	Information
Product Name	5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid
CAS No.	849068-61-7
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Bromo-3-carboxy-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 849068-61-7; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 849068-61-7); 5-Bromo-3-carboxy-7-azaindole; 5-Bromo-7-azaindole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storage under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.