Description

Diethyl 4-[5-(1,3-Benzothiazol-2-Yl)Furan-2-Yl]-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in pharmaceutical and agrochemical research. Its unique molecular architecture, featuring fused benzothiazole, furan, and dihydropyridine moieties, makes it a valuable scaffold for developing novel active ingredients. This product is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the synthesis of potential therapeutic agents targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, especially in oncology, neurology, and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in lead optimization programs.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Electronic Materials: Potential precursor for materials research due to the conjugated system present in the benzothiazole and furan units.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes to study enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions.

Basic Information

Product Name	Diethyl 4-[5-(1,3-Benzothiazol-2-Yl)Furan-2-Yl]-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS No.	848919-95-9
Molecular Formula	C26H24N2O5S
Molecular Weight	476.55 g/mol
Synonyms	4-[5-(1,3-Benzothiazol-2-yl)furan-2-yl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester; Diethyl 4-(5-(benzo[d]thiazol-2-yl)furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-[5-(2-Benzothiazolyl)-2-furanyl]-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester; CAS 848919-95-9; Benzothiazole-furan-dihydropyridine derivative
EINECS	Contact for details

Quality Control

Our Diethyl 4-[5-(1,3-Benzothiazol-2-Yl)Furan-2-Yl]-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.