Description

2-(Bromomethyl)-3-Methoxy-6-Methylpyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functional organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The bromomethyl group is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Alkylation Agent: Acts as an efficient alkylating agent in nucleophilic substitution reactions to introduce methoxymethylpyridine motifs.

Basic Information

Product Name	2-(Bromomethyl)-3-Methoxy-6-Methylpyridine
CAS No.	848696-31-1
Molecular Formula	C8H10BrNO
Molecular Weight	216.07 g/mol
Synonyms	3-Methoxy-6-methyl-2-pyridinemethanol, bromo derivative; 2-Bromomethyl-3-methoxy-6-methylpyridine; 3-Methoxy-2-(bromomethyl)-6-methylpyridine; 6-Methyl-3-methoxy-2-pyridinemethyl bromide; (3-Methoxy-6-methyl-2-pyridinyl)methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3-Methoxy-6-Methylpyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by IR, NMR), and impurity profiles. Our quality assurance protocols are designed to support regulatory filings and ensure batch-to-batch consistency for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.