Description

2-Morpholin-4-Yl-Isonicotinic Acid Hydrochloride is a high-purity chemical building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key synthon for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly in therapeutic areas requiring morpholine and isonicotinic acid scaffolds.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new molecular entities.
• API Synthesis: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological pathways and target validation.
• Fine Chemical Production: Employed in the manufacture of specialty and custom fine chemicals for advanced applications.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for client-specific synthesis projects and scale-up activities.

Basic Information

Product Name	2-Morpholin-4-Yl-Isonicotinic Acid Hydrochloride
CAS No.	848580-46-1
Molecular Formula	C10H13ClN2O3
Molecular Weight	244.68 g/mol
Synonyms	2-(Morpholin-4-yl)isonicotinic acid hydrochloride; 4-(4-Pyridinyl)-2-morpholinecarboxylic acid hydrochloride; 2-Morpholinoisonicotinic acid hydrochloride; Isonicotinic acid, 2-morpholino-, hydrochloride; 2-(4-Morpholinyl)isonicotinic acid HCl; 848580-46-1; 2-Morpholin-4-yl-isonicotinic acid HCl
EINECS	Contact for details

Quality Control

Our 2-Morpholin-4-Yl-Isonicotinic Acid Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.