Description

2,8-Diazaspiro[4.5]Decan-1-One, 2-Methyl-, Hydrochloride (1:1) is a high-purity, spirocyclic organic compound supplied as a hydrochloride salt. This specialized building block is of significant value in modern pharmaceutical research and development, particularly for its role in constructing complex molecular architectures. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic and bridged heterocyclic compounds during lead optimization and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Serves as a starting material or advanced intermediate for the kilogram-scale synthesis of potential APIs under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Employed in the synthesis of tool compounds and molecular probes for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decan-1-One, 2-Methyl-, Hydrochloride (1:1)
CAS No.	848580-34-7
Molecular Formula	C9H17ClN2O
Molecular Weight	204.70 g/mol
Synonyms	2-Methyl-2,8-diazaspiro[4.5]decan-1-one hydrochloride; 2-Methyl-1-oxa-2,8-diazaspiro[4.5]decane hydrochloride; 2-Methyl-2,8-diazaspiro[4.5]decan-1-one HCl; 1-Oxa-2,8-diazaspiro[4.5]decane, 2-methyl-, hydrochloride; 848580-34-7; 2-Methyl-2,8-diazaspiro[4.5]decan-1-one monohydrochloride
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decan-1-One, 2-Methyl-, Hydrochloride (1:1) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.