Description

3-Bromo-6-Chloropyridin-2-Ol is a halogenated pyridinol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents on the pyridine ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core is a common motif.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-6-Chloropyridin-2-Ol
CAS No.	848423-85-8
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	2-Hydroxy-3-bromo-6-chloropyridine; 3-Bromo-6-chloro-2-pyridinol; 6-Chloro-3-bromopyridin-2-ol; 3-Bromo-6-chloro-2-hydroxypyridine; 2-Pyridinol, 3-bromo-6-chloro-; 848423-85-8; 3-Bromo-6-chloro-2(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Chloropyridin-2-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by techniques such as HPLC, NMR, and GC is supplied with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.