Description

2-Methoxy-3-Chloro-5-Bromopyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with tailored activity.
• Ligand and Catalyst Development: Used to create sophisticated pyridine-based ligands for transition metal catalysis.
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	2-Methoxy-3-Chloro-5-Bromopyridine
CAS No.	848366-28-9
Molecular Formula	C6H5BrClNO
Molecular Weight	222.47 g/mol
Synonyms	3-Chloro-5-bromo-2-methoxypyridine; 5-Bromo-3-chloro-2-methoxypyridine; 2-Methoxy-3-chloro-5-bromopyridine; Pyridine, 3-chloro-5-bromo-2-methoxy-; 848366-28-9
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-Chloro-5-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.