Description

5-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid CAS NO 848308-47-4 is a high-purity, protected amino acid derivative featuring a pyridine core and a Boc-protected amine group. This compound is a critical building block in modern organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and oncological pathways.
• Peptide Mimetics & Drug Discovery: Used to incorporate the pyridine-2-carboxylic acid scaffold into peptide backbones, creating novel enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Chemical Biology Research: Utilized in the design and synthesis of molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a protected, bifunctional pyridine derivative.

Basic Information

Item	Detail
Product Name	5-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid
CAS No.	848308-47-4
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]picolinic acid; 5-[(Boc)amino]pyridine-2-carboxylic acid; 5-(Boc-amino)-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-5-Apca; tert-Butyl (6-carboxypyridin-3-yl)carbamate; 5-(Boc-amino)picolinic acid; 5-Amino-2-pyridinecarboxylic acid tert-butyl carbamate
EINECS	Contact for details

Quality Control

Our 5-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for GMP-grade intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.