Description

2-Bromo-3-Iodo-Isonicotinic Acid is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Ligand Synthesis: Building block for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Material Science: Intermediate for the synthesis of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Bromo-3-Iodo-Isonicotinic Acid
CAS No.	848243-29-8
Molecular Formula	C6H3BrINO2
Molecular Weight	327.90 g/mol
Synonyms	3-Iodo-2-bromoisonicotinic acid; 2-Bromo-3-iodopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-bromo-3-iodo-; Isonicotinic acid, 2-bromo-3-iodo-; 848243-29-8; AI3-31855; BRN 3121925; SCHEMBL218062
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Iodo-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our standard is to supply material with a typical purity of ≥97% (HPLC), with higher grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive; containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.