Description

6-(2,2-Dimethyl-Propionylamino)-Pyridine-2-Carboxylic Acid Hydrochloride is a high-purity, non-natural amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides and fungicides with tailored activity profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in medicinal chemistry to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring specific, high-value pyridine-carboxylic acid derivatives.

Basic Information

Product Name	6-(2,2-Dimethyl-Propionylamino)-Pyridine-2-Carboxylic Acid Hydrochloride
CAS No.	848243-27-6
Molecular Formula	C11H15ClN2O3
Molecular Weight	258.70 g/mol
Synonyms	6-(2,2-Dimethylpropanamido)picolinic acid hydrochloride; 6-Pivalamidopicolinic Acid Hydrochloride; 6-[(2,2-Dimethylpropanoyl)amino]pyridine-2-carboxylic acid hydrochloride; Piv-Pic-OH·HCl; 2-Pyridinecarboxylic acid, 6-[(2,2-dimethyl-1-oxopropyl)amino]-, hydrochloride (1:1); 6-(Pivaloylamino)-2-pyridinecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 6-(2,2-Dimethyl-Propionylamino)-Pyridine-2-Carboxylic Acid Hydrochloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.