Description

2-Isopropoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is a high-value, synthetically versatile boronic ester derivative of pyridine. This compound matters as a critical building block in modern organic synthesis, enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. Pharmaceutical, agrochemical, and advanced materials researchers need this intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products with improved efficacy.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for palladium-catalyzed coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology Probes: Enables the labeling and study of biological systems through its reactive boronate handle.
• Ligand Synthesis: Intermediate for creating complex chelating ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Isopropoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine
CAS No.	848243-25-4
Molecular Formula	C14H22BNO3
Molecular Weight	263.14 g/mol
Synonyms	2-Isopropoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isopropoxypyridine; 2-(2-Isopropoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pyridine, 2-isopropoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 848243-25-4; Boronic acid, (2-isopropoxy-3-pyridinyl)-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 2-Isopropoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.