Description

5-Bromo-3-Iodo-2-Isopropoxy-Pyridine is a high-value, multi-halogenated pyridine derivative used as a key synthetic intermediate in advanced organic chemistry. This compound matters for its unique substitution pattern, which provides multiple reactive sites for selective cross-coupling reactions, enabling the construction of complex heterocyclic architectures. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a precursor for functionalized ligands and organic electronic materials due to the pyridine core and halogen handles.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, where the bromine and iodine atoms offer differential reactivity.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex, poly-substituted pyridine libraries for screening purposes.

Basic Information

Product Name	5-Bromo-3-Iodo-2-Isopropoxy-Pyridine
CAS No.	848243-21-0
Molecular Formula	C8H9BrINO
Molecular Weight	341.97 g/mol
Synonyms	2-Isopropoxy-5-bromo-3-iodopyridine; 3-Iodo-5-bromo-2-isopropoxypyridine; 5-Bromo-3-iodo-2-(propan-2-yloxy)pyridine; Pyridine, 5-bromo-3-iodo-2-(1-methylethoxy)-; 848243-21-0; 5-Br-3-I-2-iPrO-Py
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-2-Isopropoxy-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.